My Life in Transition is a second anthology of Kaye’s web comic, Up and Out, chronicling her life as a transgender woman. Kaye publishes nearly one three-panel comic a day, and this collection is roughly six months of her life. In it, Kaye explores dating as a trans woman, both men and women, and healing after a long-term relationship ends. Kaye also shows instances of people misgendering her, and the anxiety and dysmorphia that often follows. Kaye also navigates friendships and builds personal boundaries with friends, romantic partners, and work. Kaye also struggles with her bio family who is not supportive and exhibits transphobia. A friend suggests a chosen family - building a family of people who are supportive and positive influences. Kaye builds a chosen family of other trans individuals and friends who see Kate for who she is.

Kiku is a high schooler on vacation with her mother in San Francisco, trying to find their family home in Japantown, when she gets swept back in time to her grandmother's violin recital. She travels back and forth a few more times before she is sent back to 1942, right as her grandmother's family is being shipped out to an incarceration camp. She is "stuck" in the past for a year, living in the camps alongside other Nikkei and her grandmother, who she doesn't have the courage to speak to.  Back in the present, Kiku and her mother decide to research more of the family's history and the history of the Topaz, Utah camp, and to become activists against the camps at the U.S. Border for Latinx immigrants.